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Learn About Allografts

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Mineralized image
Product Details

Mineralized

Mineralized bone allografts provide a scaffold, which is necessary for cellular migration and attachment.1,2 Cells need to be able to move onto and attach to a scaffold to encourage bone fusion. These allografts come in a wide variety of forms including bone void fillers such as chips, particulate, fibers, and cubes, as well as structural grafts designed to provide support upon implantation. Examples of structural grafts include interbody spine spacers, struts, shafts, and wedges.

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  • Osteoconductive: Natural bone matrix facilitates cell attachment and proliferation, and vascular in-growth
  • Available in cortical only, cancellous only, or corticocancellous
  • Many different shapes, sizes, and functional purposes are available

COMPARISON OF GRAFT PROPERTIES

 

Osteoconductive   
 

Osteoinductive   
 

Osteogenic   
 

Mineralized Bone Allografts

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Demineralized Bone Matrixtick icontick icon 
Cellular Bone Matrixtick icontick icontick icon
Autograft*tick icontick icontick icon
Syntheticstick icon  
Recombinant Proteins tick icon 
Combination Graftstick icontick icon 
Xenografttick icon  

*Autograft is partially demineralized, and therefore its osteoinductivity (signals) are unenhanced compared to grafts with fully demineralized bone.

  • Non-structural mineralized allografts can be used as extenders for autograft
  • Non-structural mineralized allografts can be used as bone void fillers for patients who do not require advanced properties
  • Structural mineralized allografts can provide immediate support, such as in the spinal column

References

References
  1. Baldwin P, Li DJ, Auston DA, Mir HS, Yoon RS, Koval KJ. Autograft, Allograft, and Bone Graft Substitutes: Clinical Evidence and Indications for Use in the Setting of Orthopaedic Trauma Surgery. J Orthop Trauma. 2019 Apr;33(4):203-213. doi: 10.1097/BOT.0000000000001420. PMID: 30633080.
  2. Wang W, Yeung KWK. Bone grafts and biomaterials substitutes for bone defect repair: A review. Bioactive Materials/ 2017; 2(4); 224-247. ISSN 2452-199X. https://doi.org/10.1016/j.bioactmat.2017.05.007.